Super Resolution Imaging

Super-resolution imaging is at the heart of my research, where I focus on computational methods to overcome the diffraction limits of traditional optical microscopy. This field has transformative potential, enabling the visualization of cellular and molecular structures with unprecedented detail. I am particularly interested in developing deep learning-based solutions that efficiently upscale low-resolution microscopy images while preserving critical features and reducing artifacts.

My work emphasizes algorithmic solutions, making super-resolution imaging accessible without the need for expensive or complex hardware modifications. These innovations have the potential to enhance our understanding of cellular structures and molecular dynamics in fields like biology, materials science, and biophysics.

Research Highlights

  • Developing advanced deep learning models, including transformer-based architectures, to upscale low-resolution images and accurately reconstruct fine spatial details. (Dutta et al., 2025)

  • Exploring traditional techniques, such as interpolation and iterative back-projection, to benchmark performance against modern computational methods.

  • Applying these techniques to various microscopy modalities, such as fluorescence and confocal microscopy, with applications in cell biology, material science, and biophysics.

  • Evaluating the impact of super-resolution methods using quantitative metrics like SSIM and PSNR to ensure reliable and reproducible results.

References

2025

  1. arXiv
    State-of-the-Art Transformer Models for Image Super-Resolution: Techniques, Challenges, and Applications
    Debasish Dutta, Deepjyoti Chetia, Neeharika Sonowal, and 1 more author
    arXiv preprint arXiv:2501.07855, 2025
     https://doi.org/10.48550/arXiv.2501.07855
    ArXiv preprint